Search results for "arterial oxygen tension"
showing 3 items of 3 documents
Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG …
2017
Background Little information is available about the geo-economic variations in demographics, management, and outcomes of patients with acute respiratory distress syndrome (ARDS). We aimed to characterise the effect of these geo-economic variations in patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE). Methods LUNG SAFE was done during 4 consecutive weeks in winter, 2014, in a convenience sample of 459 intensive-care units in 50 countries across six continents. Inclusion criteria were admission to a participating intensive-care unit (including transfers) within the enrolment window and receipt of invasive or non…
Effect of arterial oxygen tension on cerebral blood flow at different levels of arterial PCO2.
1970
Die Wirkung des arteriellen O2-Partialdruckes auf die Durchblutung des Grosshirns, Kleinhirns und Hirnstammes bei normalen und erhohten CO2-Partialdrucken im arteriellen Blut wird an der anaesthesierten Katze untersucht. Die Wirkung des PaO2 ist von der Hohe des PaCO2 abhangig.
The Significance of Low O2-Tensi0ns in the Brain Cortex for Occurrence of Metabolic Alterations under Critical Flow Conditions
1985
A reduction in the 02 supply to the brain cortex leads to O2 deficiency and curtailment of neuronal metabolism and function as soon as a minimal cellular O2 tension of 0.1 – 1 mmHG (13 – 133 Pa) can no longer be maintained (Chance et al., 1964; Grote 1967). The hypoxia-induced metabolic alterations are characterized by decreased tissue levels of the energy-rich phosphate compounds PCr and ATP. In addition, elevated concentrations of lactate, pyruvate and NADH and an increase in the lactate/pyruvate ratio and in the NADH/NAD+ ratio are to be expected (Duffy et al., 1972; Granholm and Siesjo 1969; Granholm et al., 1969; Granholm and Siesjo 1971; Grote 1978; Grote and Schubert 1982; Norberg an…